个人简介

      医学博士，硕士/博士生导师，现任Williamhill中文组胚细胞系师生党支部书记、组织胚胎学教研室主任、基础医学实验教学中心形态学实验室主任。2015年-2016年在美国印第安纳大学医学院神经科学研究中心做访问学者。作为主持人已获得国家自然科学基金和广东省自然科学基金多项，作为主要合作者参与了国家自然科学基金重大项目和重点项目，国家科技部重点研发项目等多项基金。获广东省自然科学奖二等奖等（排名2），发表相关学术论文60余篇，其中SCI收录论文43篇。

研究方向

  1. 干细胞源性神经组织移植联合电刺激/电针修复脊髓损伤的机制研究
  2. 电刺激联合负载干细胞的生物材料桥接修复缺损外周神经的机制研

近5年发表的学术论文（#第一作者; *通讯作者）：

  1. Xu j#, Y Yang Y#, ChenZ#, ...  Yuan-Shan Zeng*,  Ying Ding*, Bi-Qin Lai*. rTMS-induced motor cortex activation drives neural network tissueoid mediated spinal motor neural pathway reconstruction. Theranostics2026; 16(2):915-935. doi:10.7150/thno.117789
  2. Yu Cheng#, Fan-qi Meng#, Zhan-mou Liang, Xin Zhou, Wenya Pei, Jingwen Ruan, Xiaozhou Lu, Ying Ding*, Guanheng He*. Combination of Governor Vessel and local acupoints electroacupuncture to improve the repair based on nerve conduit of long segment median nerve defect. IBRO Neurosci Rep,2025 May 18:18:814-822.
  3. Liu JL#, Chen ZH#, Wu RJ, Yu HY, Yang SB, Xu J, Wu CR, Guo YN, Hua N, Zeng X, Ma YH, Li G, Zhang L, Chen YF, Zeng YS*, Ding Y*, Lai BQ*. Effects of tail nerve electrical stimulation on the activation and plasticity of the lumbar locomotor circuits and the prevention of skeletal muscle atrophy after spinal cord transection in rats. CNS Neurosci Ther. 2024 Mar;30(3):e14445.
  4. Zhang RY, Wang JH, Deng QW, Xiao XR, Zeng X, Lai B, Li G, Ma Y, Ruan J, Han I, Zeng YS*, Ding Y*. MSCs combined with electroacupuncture treatment regulate the subpopulation of macrophages and astrocytes to facilitate axonal regeneration in transected spinal cord. Neurospine 2023;20(4):1358-1379. 
  5. Ding Y*, Li G*, Zhang P and Zhang W (2023) Editorial: New advances in functional rehabilitation after central and peripheral nervous system injury. Front. Neurol. 14:1160382. doi: 10.3389/fneur.2023.1160382
  6. Xiao X#, Deng Q#, Zeng X, Lai BQ, Ma YH, Li G, Zeng YS, Ding Y*. Transcription Profiling of a Revealed the Potential Molecular Mechanism of Governor Vessel Electroacupuncture for Spinal Cord Injury in Rats. Neurospine. 2022, 19(3):757-769.
  7. Pei W, Meng F, Deng Q, Zhang B, Gu Y, Jiao B, Xu H, Tang J, Zhou X, Li Z, He G, Ruan JW*, Ding Y*. Electroacupuncture promotes the survival and synaptic plasticity of hippocampal neurons and improvement of sleep deprivation-induced spatial memory impairment. CNS Neurosci Ther. 2021, 27(12):1472-1482.
  8. Yang Y#, Xu HY#, Deng QW, Wu GH, Zeng X, Jin H, Wang LJ, Lai BQ, Li G, Ma YH, Jiang B, Ruan JW, Wang YQ, Ding Y*, Zeng YS*. Electroacupuncture facilitates the integration of a grafted TrkC-modified mesenchymal stem cell-derived neural network into transected spinal cord in rats via increasing neurotrophin-3. CNS Neurosci Ther. 2021, 27(7): 776-791.
  9. Xu H#, Yang Y#, Deng QW, Zhang BB, Ruan JW, Jin H, Wang JH, Ren J, Jiang B, Sun JH, Zeng YS*, Ding Y*. Governor Vessel electro-acupuncture promotes the intrinsic growth ability of spinal neurons through activating CGRP/αCaMKII/NT-3 pathway after spinal cord injury. Journal of Neurotrauma, 2021, 38(6):734-745.
  10. 成豫，邓青文，黄爽，田淼，李雪莉，赖碧琴，谢曦，曾园山，丁英(通讯作者)*. 硬膜外电刺激促进大鼠夹伤脊髓的神经元存活和神经纤维侧支出芽 [J]. 解剖学研究，2025，47(02):115-121.
  11. 张宝宝, 岑晓晴，曾园山，丁英(通讯作者). 神经示踪定位SD大鼠长下行脊髓固有神经元胞体及其轴突投射的解剖位置. 解剖学研究，2021，43（1）:1-6.
  12. 彭历芝，位庆帅，马瑗锾，许金海，蒋 斌，曾园山，曾 湘，丁英(通讯作者)*. 构建具有突触传递潜能的iPSC源性抑制性神经网络组织. william威廉英国学报（医学科学版）. 2023, 44(1):18-25
  13. Zeng YS, Ding Y, Xu HY, Zeng X, Lai BQ, Li G, Ma YH. Electro-acupuncture and its combination with adult stem cell transplantation for spinal cord injury treatment: A summary of current laboratory findings and a review of literature. CNS Neurosci Ther. 2022, 28(5): 635-647. 
  14. Lai Biqin#, Wu Rongjie#, Han Weitao#, Bai YR, Liu JL, Yu HY, Yang SB, Wang LJ, Ren JL, Ding Y, Li G, Zeng X, Ma YH, Quan Q, Xing LY, Jiang B, Wang YQ, Zhang L, Chen ZH, Zhang HB, Chen YF, Zheng QJ, Zeng YS*. Tail nerve electrical stimulation promoted the efficiency of transplanted spinal cord-like tissue as a neuronal relay to repair the motor function of rats with transected spinal cord injury. Biomaterials 2023, 297, 122103.
  15. Lai BQ, Zeng X, Han WT, Che MT, Ding Y, Li G, Zeng YS. Stem cell-derived neuronal relay strategies and functional electrical stimulation for treatment of spinal cord injury. Biomaterials, 2021 Dec;279:121211.
  16. Li G, Zhang B, Sun JH, Shi LY, Huang MY, Huang LJ, Lin ZJ, Lin QY, Lai BQ, Ma YH, Jiang B, Ding Y, Zhang HB, Li MX, Zhu P, Wang YQ, Zeng X, Zeng YS. An NT-3-releasing bioscaffold supports the formation of TrkC-modified neural stem cell-derived neural network tissue with efficacy in repairing spinal cord injury. Bioactive Materials, 2021, 6:3766-3781.
  17. Ma YH, Shi HJ, Wei QS, Deng QW, Sun JH, Liu Z, Lai BQ, Li G, Ding Y, Niu WT, Zeng YS, Zeng X. Developing a mechanically matched decellularized spinal cord scaffold for the in situ matrix-based neural repair of spinal cord injury. Biomaterials, 2021, 279:121192
  18. Bai YR, Lai BQ, Han WT, Sun JH, Li G, Ding Y, Zeng X, Ma YH, Zeng YS. Decellularized optic nerve functional scaffold transplant facilitates directional axon regeneration and remyelination in the injured white matter of the rat spinal cord. Neural Regen Res. 2021 Nov;16(11):2276-2283. 
  19. Lai BQ, Bai YR, Han WT, Zhang B, Liu S, Sun JH, Liu JL, Li G, Zeng X, Ding Y, Ma YH, Zhang L, Chen ZH, Wang J, Xiong Y, Wu JH, Qi Q, Xing LY, Zhang HB, Zeng YS. Construction of a niche-specific spinal white matter-like tissue to promote directional axon regeneration and myelination for rat spinal cord injury repair. Bioactive Materials, 2021, Oct 20;11:15-31.

获奖荣誉

  1. 组织工程神经类组织移植修复脊髓损伤的中继作用机制研究, 获2024年度广东省科学技术奖自然科学奖二等奖，排名7/10
  2. 督脉经穴电针通过NT-3介导移植的成体干细胞修复脊髓损伤的研究, 获2017年度广东省科学技术奖自然科学奖二等奖，排名第2/10
  3. 督脉经穴电针通过NT-3介导移植的成体干细胞修复脊髓损伤的研究，2021年度中华中医药学会科学技术奖三等奖，排名第2/8
  4. 移植干细胞源性神经网络组织修复脊髓损伤的系列研究，第四届广东医学科技奖 一等奖，排名第6，2022年12月