个人简介

Williamhill中文副教授，硕士生导师。本科毕业于南方医科大学，博士毕业于william威廉英国，获医学博士学位。2014年至2022年在Williamhill中文从事专职科研工作（博士后及特聘研究员）。致力于干细胞再生医学和中枢神经损伤修复研究，涉及到干细胞、核酸类药物、生物活性材料、神经刺激等前沿交叉学科的融合，发表第一/通讯作者（含共同）中科院一区Top SCI论文11篇，已建立稳定的科研团队，主持5项国家级课题，包括国家科技部重点研发青年科学家项目1项，国家科技部重点研发课题1项（获优秀结题评价），国家自然科学基金3项；获广东省杰出青年基金、中国科协青年人才托举工程项目、william威廉英国逸仙学者-新锐学者；主持广东省和广州市科技基金各一项。

近5年发表的学术论文

【代表性学术论著】

  1. Lai, B.Q., Wu, R.J., Wu, C.R., Yu, H.Y., Xu, J., Yang, S.B., Chen, Z.H., Li, X., Guo, Y.N., Yang, Y., Che, M.T., Wu, T.T., Fu, G.T., Yang, Y.H., Chen, Z., Hua, N., Liu, R., Zheng, Q.J., Chen, Y.F., 2025. DON-Apt19S bioactive scaffold transplantation promotes in situ spinal cord repair in rats with transected spinal cord injury by effectively recruiting endogenous neural stem cells and mesenchymal stem cells. Materials today. Bio 32, 101753. (第一作者兼共同通讯, IF: 10.2，中科院1区)
  2. Wu, R.-J., Liu, J.-L., Chen, Z.-H., Xu, J., Ding, Y., Yu, H.-Y., Wu, C.-R., Yang, S.-B., Liu, R., Guo, Y.-N., Yang, Y., Wu, T.-T., Fu, G.-T., Li, G., Sun, J.-W., Lin, Y.-J., Tian, M., Cheng, Y., Lv, M.-Y., Chen, Z., Zheng, Q.-J., Chen, Y.-F., Lai, B.-Q., 2025. The recruitment of alkaline phosphatase-positive endogenous neural stem cells enables robust neurogenesis and neural pathways reconstruction following spinal cord injury. Chemical Engineering Journal 513, 162988. (最后通讯, IF: 13.2，中科院1区)
  3. Liu JL, Chen ZH, Wu RJ, Yu HY, Yang SB, Xu J, Wu CR, Guo YN, Hua N, Zeng X, Ma YH, Li G, Zhang L, Chen YF, Zeng YS, Ding Y, Lai BQ. Effects of tail nerve electrical stimulation on the activation and plasticity of the lumbar locomotor circuits and the prevention of skeletal muscle atrophy after spinal cord transection in rats. CNS neuroscience & therapeutics. 2023;00:1–20. (最后通讯, IF: 5.5，中科院2区)
  4. Liu JL, Wang S, Chen ZH, Wu RJ, Yu HY, Yang SB, Xu J, Guo YN, Ding Y, Li G, Zeng X, Ma YH, Gong YL, Wu CR, Zhang LX, Zeng YS, Lai BQ. The therapeutic mechanism of transcranial iTBS on nerve regeneration and functional recovery in rats with complete spinal cord transection. Frontiers in immunology. 2023, 4, 1153516. (最后通讯, IF:7.3，中科院2区)
  5. Lai BQ, Wu RJ, Han WT, Bai YR, Liu JL, Yu HY, Yang SB, Wang LJ, Ren JL, Ding Y, Li G, Zeng X, Ma YH, Quan Q, Xing LY, Jiang B, Wang YQ, Zhang L, Chen ZH, Zhang HB, Chen YF, Zheng QJ, Zeng YS. Tail nerve electrical stimulation promoted the efficiency of transplanted spinal cord-like tissue as a neuronal relay to repair the motor function of rats with transected spinal cord injury. Biomaterials. 2023, 297:122103. (共同第一作者, IF: 14.0，中科院1区)
  6. Lai BQ, Zeng X, Han WT, Che MT, Ding Y, Li G, Zeng YS. Stem cell-derived neuronal relay strategies and functional electrical stimulation for treatment of spinal cord injury. Biomaterials. 2021, 279: 12121. (第一作者, IF: 14.0，中科院1区)
  7. Lai BQ, Bai YR, Han WT, Zhang B, Liu S, Sun JH, Liu JL, Li G, Zeng X, Ding Y, Ma YH, Zhang L, Chen ZH, Wang J, Xiong Y, Wu JH, Qi Q, Xing LY, Zhang HB, Zeng YS. Construction of a niche-specific spinal white matter-like tissue to promote directional axon regeneration and myelination for rat spinal cord injury repair. Bioactive Materials, 2021, 20;11:15-31.(共一兼共同通讯作者, IF：16.8，中科院1区).
  8. Bai YR, Lai BQ, Han WT, Sun JH, Li G, Ding Y, Zeng X, Ma YH, Zeng YS. Decellularized optic nerve functional scaffold transplant facilitates directional axon regeneration and remyelination in injured white matter of rat spinal cord. Neural regeneration research. 2021 Nov;16(11):2276-2283. (IF：6.0, 共一兼共同通讯作者，中科院2区) 

获奖荣誉

  1. 广东省科学技术奖二等奖，2024；组织工程神经类组织移植修复脊髓损伤的中继作用机制研究。（曾园山，曾湘，赖碧琴，李戈，吴武田，马瑗锾，丁英，蒋斌，张宏波，车明天）。
  2. 广东省医学科学技术奖一等奖, 2023; 移植干细胞源性神经网络组织修复脊髓损伤的系列研究（GDMA202204106）, (曾园山; 曾湘; 赖碧琴; 李戈; 马瑗锾; 丁英; 吴武田; 车明天; 张可; 金辉; 邱学成; 张玉婷)。

学术兼职

任中国解剖学会青年工作委员会常务委员和中国研究型医院学会神经再生与修复专业委员会委员。